CaBP Data Library General Information

S100A5/S100D

Primary information about S100A5/S100D:
Basic chemical and physical information
Basic biological information
Basic genomic information
Metal ion binding constants
Interspecies sequence alignment
Information on function
Summary of structural studies
Information on the conformational change List of available structures Information about mutations
References about S100A5 Other web resources about S100A5

Basic Information

Additional names and abbreviations: No additional names are stored in the database
Isoforms: No information about isoforms is stored in the database
Yeast Protein Database Entries: No links to the YPD are stored in the database


Basic Chemical and Physical Information:
Number of amino acids: 93 (Mus musculus) - 110 (Homo sapiens)
View a list of all sources stored in the database
Molecular weight: 10.812 kD (Mus musculus) - 12.813 kD (Homo sapiens)
View a list of all sources stored in the database
pI: calculated pI (Homo sapiens) = 5.2 (InfoCard)
Number of functional calcium binding sites: not yet available in the data library
Macroscopic calcium binding constants: not yet available in the data library
Other metal binding constants: not yet available in the data library
Protein stability: not yet available in the data library
Post-translational modifications: not yet available in the data library


Basic Biological Information:
Source organisms: Homo sapiens, Mus musculus
View an annotated list of all sources stored in the database
Tissues: not yet available in the data library
Subcellular localization: not yet available in the data library
Regulation: not yet available in the data library


Genomic Information:
GenBank entries: View a list of GenBank entries stored in the database
Gene length: not yet available in the data library
Gene structure: Homo sapiens, expressed: GenBank codes Z18950, Z18949; intron 1 is in the 5'-untranslated region, intron 2 precedes residue 13, intron 3 precedes residue 64 (InfoCard)
Promoter: not yet available in the data library
Gene copies: not yet available in the data library
Alleles: Homo sapiens: D72E (InfoCard)
Chromosomal localization: Homo sapiens, expressed (GenBank code Z18949): q21 region of chromosome 1 (part of the cluster of S100 protein genes) (InfoCard)

Interspecies Sequence Alignment



                                     |-helixA-|--loop1------|helixB|
                                      En**nn**nX**Y*Z**#Ix**zn**nn*n

HUMAN   : MPAAWILWAHSHSELHTVMETPLEKALTTMVTTFHKYSGREGSKLTLSRKELKELIKK 


                    |-helixC-|--loop2-----|helixD|
                    En**nn**nX*Y*ZG#Ix**zn**nn*n

HUMAN   : ELCLGEMKESSIDDLMKSLDKNSDQEIDFKEYSVFLTMLCMAYNDFFLEDNK


Sequence alignment of the entire S100 subfamily

Functional Information:

General information:

Biological roles:

Disease states:

Target molecules:


Structural Information:

Calcium-coordination:
not yet available in the data library


Nature of the conformational changes:
not yet available in the data library


Secondary structure:
(as reported in the PDB file and its accompanying reference)
not yet available in the data library


Additional structural information:
no additional structural information is currently stored in the database


Available structures:
(follow the links from the PDB code to the retrieve the
PDB files)
no structures are currently stored in the database

Information about mutants: